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CRESEMBA® offers linear and predictable PKs, and therapeutic drug monitoring is not routinely recommended1–5
Unlike other azoles, CRESEMBA® has a linear PK profile and low inter- and intra-patient variability.1–4,a Furthermore, the absorption of oral CRESEMBA® is unaffected by food or mucositis.1,6
CRESEMBA® has good tissue penetration, allowing maintenance of therapeutic concentrations in the body for a long period of time,7,8 with predictable PKs for reliable treatment when patients need it most.1,2
With both IV and oral formulations, the long half-life (56–104 hours) of CRESEMBA® allows for convenient once-daily maintenance dosing.1,3 Therapeutic drug monitoring may be needed in some cases but is not routinely recommended4,5 – helping to avoid inadequate exposure and facilitate long-term treatment at home.9,10
a. Up to 600 mg/day.1; PK, pharmacokinetic.
Prescribing Information:
CRESEMBA® (isavuconazole)
References:
PP-CRB-IND-0472 July 2022
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