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AboutIntroducing Enbrel®Heritage of Enbrel®IndicationsTherapeutic IndicationsRheumatoid ArthritisJuvenile Idiopathic ArthritisPsoriatic ArthritisAxial SpondyloarthritisPsoriasis & Paediatric PsoriasisMechanism of actionMode of ActionHalf-lifeDosingDosingRheumatoid Arthritis, Psoriatic Arthritis & Axial SpondyloarthritisJuvenile Idiopathic ArthritisPsoriasisPaediatric PsoriasisAdministration & StorageAdministrationMYCLIC®StorageEfficacy & SafetyEfficacyRapid EffectivenessSustained EffectivenessEffectiveness With Monotherapy or Combination TherapySafetyTolerability Across IndicationsSummary of Prescribing InformationImmunogenicityImmunogenicity & Clinical ResponseImmunogenicity & Enbrel®Experience & InsightsExperience & InsightManufacturingPatient StoriesRheumatoid ArthritisPatient With an Increased Risk of Serious InfectionsMTX-IR PatientPatient Who Is Considering Starting a FamilyElderly-onset RA PatientYoung Patient Worried About the Lifelong Impact of RAYoung Patient Worried About Treatments That Lose Effectiveness Over TimeJuvenile Idiopathic ArthritisJuvenile PatientPatient Moving From Childhood to AdolescenceAxial SpondyloarthritisAS Patients With Heel EnthesitisAS Patients With Functional LimitationsAdvanced AS PatientsPsoriatic Arthritis & PsoriasisPsO Patient With Severe SymptomsPsO Patients With Cyclical SymptomsPsA Patient With Metabolic SyndromePsA Patient With Multiple Skin & Joint SymptomsSupport & ServicesSupport & ServicesUsing Enbrel®Summary of Prescribing InformationPatient ResourcesEventsMaterialsVideos

Enbrel® (etanercept)

Transforming patients’ lives today and tomorrow¹

  

Enbrel® is a TNFi approved for treating multiple chronic diseases in rheumatology and dermatology.2

  • Celebrating 21 years of timeless trust3
     
  • Experience of over 6 million patient-years3
     
  • Clinically proven, backed up with more than 500 clinical trials4
     
  • Accredited with more than 7000 published articles5

  

Heritage of Enbrel®

     

Approved by the EMA in 2000,6 Enbrel® was the first-approved TNFi in RA.1

  

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Indications

Enbrel® is approved across 6 therapeutic indications, including paediatric indications.²

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Efficacy & Safety

The efficacy and safety profile of Enbrel® has been established across 
indications.7-13

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Patient Stories

What type of patients may be the best candidates for Enbrel® therapy?

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Manufacturing

Patient access to Enbrel® starts with a complex and highly controlled manufacturing process.14,15

  

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Pfizer Limited

The Capital – A Wing, 1802, 18th Floor, Plot
No. C-70, G Block, Bandra Kurla Complex,
Bandra (East), Mumbai – 400 051, India.

®Trademark Proprietor – Wyeth LLC, USA
Licensed User – Pfizer Limited, India

To view the summary of prescribing
information for ENBREL
®, please
click here.

For the use only of Registered Medical
Practitioners or a Hospital or a Laboratory.
Full prescribing information available on
request.

  

*Some studies may have evaluated (or will evaluate) etanercept biosimilars and/or evaluated (or will evaluate) indications for which Enbrel® is not approved.

  

EMA, European Medicines Agency; RA, rheumatoid arthritis; TNFi, tumour necrosis factor inhibitor.

  

References:

Scott LJ. Etanercept: a review of its use in autoimmune inflammatory diseases. Drugs. 2014;74(12):1379-1410.Enbrel. Local product document. Version LPDENB062021.PERIODIC SAFETY UPDATE REPORT 26 for ACTIVE SUBSTANCE: ETANERCEPT. Etanercept Reporting Period Periodic Safety Update Report (PSUR) 26. Pfizer. 2019; 1-951. Etanercept. Search results. NIH, U.S. National Library of Medicine. Accessed on July 19, 2022. https://clinicaltrials.gov/ct2/results?cond=&term=etanercept&cntry=&state=&city=&dist=Etanercept. Search Results. NIH, National Library of Medicine. National Center for Biotechnology Information. PubMed. Accessed on July 19, 2022. https://pubmed.ncbi.nlm.nih.gov/?term=etanerceptEPAR summary for the public. European Medicines Agency. Accessed May 5, 2022. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR__Summary_for_the_public/human/000262/WC500027364.pdfWeinblatt ME, Bathon JM, Kremer JM, et al. Safety and efficacy of etanercept beyond 10 years of therapy in North American patients with early and longstanding rheumatoid arthritis. Arthritis Care Res (Hoboken). 2011;63(3):373-382.Horneff G, Burgos-Vargas R, Constantin T, et al. Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study. Ann Rheum Dis. 2014;73(6):1114-1122.Dougados M, Braun J, Szanto S, et al. Efficacy of etanercept on rheumatic signs and pulmonary function tests in advanced ankylosing spondylitis: results of a randomised double-blind placebo-controlled study (SPINE) [published correction appears in Ann Rheum Dis. 2011;70(7):1349]. Ann Rheum Dis. 2011;70(5):799-804.Dougados M, van der Heijde D, Sieper J, et al. Effects of Long-Term etanercept treatment on clinical outcomes and objective signs of inflammation in early nonradiographic axial spondyloarthritis: 104-week results from a randomized, placebo-controlled study. Arthritis Care Res (Hoboken). 2017;69(10):1590-1598.Mease PJ, Kivitz AJ, Burch FX, et al. Continued inhibition of radiographic progression in patients with psoriatic arthritis following 2 years of treatment with etanercept. J Rheumatol. 2006;33(4):712-721.Ortonne JP, Griffiths CEM, Daudén E, et al. Efficacy and safety of continuous versus paused etanercept treatment in patients with moderate-to-severe psoriasis over 54 weeks: the CRYSTEL study. Expert Rev Dermatol. 2008;3(6):657-665.Paller AS, Siegfried EC, Langley RG, et al. Etanercept treatment for children and adolescents with plaque psoriasis. N Engl J Med. 2008;358(3):241-251.Data on file. Manufacturing story. Pfizer. 2016.Data on file. Enbrel testing expert statement. Pfizer. 2018.

    

Please click the Prescribing Information link to view the safety and adverse events information of Enbrel®.
For the use only of Registered Medical Practitioners or a Hospital or a Laboratory.

    

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