The ICMR guidelines on the management of IAI with cefoperazone/sulbactam2
First-choice antibiotic for CA-IAI of mild-to-moderate severity2
Cefoperazone/Sulbactam 3 g IV 12 hourly for the treatment of IAI, specifically for biliary tract infections2
Cefoperazone/Sulbactam is effective in3
Adapted from Mazuski JE, et al. 2017.
The ICMR recommends cefoperazone/sulbactam 3 g IV 12 hourly for the treatment of:
Adapted from ICMR. 2019; Bharara T, et al. 2018.
Adapted from Mazuski JE, et al. 2017.
CA-IAI, community-acquired intra-abdominal infection; ESBL, extended-spectrum β-lactamase; IAI, intra-abdominal infection; ICMR, Indian Council of Medical Research; IV, intravenous; SIS, Surgical Infection Society; UTI, urinary tract infection.
References:
Magnex. Local product document. Pfizer; 2020. Version LPDMGX042020.
ICMR. Treatment Guidelines for Antimicrobial Use in Common Syndromes. 2nd ed. ICMR; 2019:1-206.
Mazuski JE, Tessier JM, May AK, et al. The Surgical Infection Society revised guidelines on the management of intra-abdominal infection. Surg Infect (Larchmt). 2017;18(1):1-76.
Bharara T, Sharma A, Gur R, Duggal SD, Jena PP, Kumar A. Comparative analysis of extended-spectrum beta-lactamases producing uropathogens in outpatient and inpatient departments. Int J Health Allied Sci. 2018;7(1):45-50.
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