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Indication: Monotherapy – Sulbactam/Cefoperazone is indicated for the treatment of the following infections when caused by susceptible organisms: Respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia, meningitis, skin and soft tissue infections, bone and joint infections, endometritis and other infections in the genital tract. MAGNEX® FORTE is indicated for a specific subset of patients (patients with immunocompromised febrile neutropenic cancer, patients who have undergone a bone marrow transplant).1
MAGNEX® has an improved PK and PD profile2,3
*Effect studied on resistant gram-negative bacilli (E. coli and P. aeruginosa).
†MIC against resistant P. aeruginosa was reduced four- to eightfold.
MIC, minimum inhibitory concentration; PD, pharmacodynamics; PK, pharmacokinetics.
References:
Magnex. Local product document. Pfizer; 2020. Version LPDMGX042020.
Singh M, Kochhar P. Optimizing pharmacokinetic/pharmacodynamics principles & role of cefoperazone- sulbactam. Pharmacologyonline. 2010;1:1074-1080.
Chandrasekar PH, Sluchak JA. In-vitro susceptibility of cefoperazone-susceptible and -resistant gram-negative rods to cefoperazone plus sulbactam, other beta-lactams, aminoglycosides and quinolone. Infection. 1991;19(1):49-53.
Please click the Prescribing Information link to view the safety and adverse events information of MAGNEX®.
For the use only of registered medical practitioner, or a hospital or a laboratory.
Recommended dosage in adult and special population
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Cefoperazone/Sulbactam is recommended as an effective and well-tolerated antibiotic
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Explore the safety profile of cefoperazone/sulbactam
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Cefoperazone/Sulbactam is more efficient in the treatment of infection
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For more details on, Who is a Registered medical practitioner*, please visit "https://cdsco.gov.in/opencms/export/sites/CDSCO_WEB/Pdf-documents/acts_rules/2016DrugsandCosmeticsAct1940Rules1945.pdf", Page No. 39, Rule 2 part (ee), last accessed on 26th April 2021.
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