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AboutAboutExtended CoveragePK and PD ProfileGood Safety ProfileGuidelines and RecommendationsDosingRecommended DosageAdultsSpecial PopulationEfficacyIntra-abdominal InfectionRisk factorClinical efficacyUrinary Tract InfectionRisk factorClinical efficacyRespiratory Tract InfectionResistance rateImpactClinical efficacyFebrile NeutropeniaRisk factorTreatmentClinical efficacySafetyClinical & Scientific DataSupport & ResourcesSupport & ResourcesClinical UpdatesPrescribing InformationVideosWebinarsExplore Materials

Indication: Monotherapy – Sulbactam/Cefoperazone is indicated for the treatment of the following infections when caused by susceptible organisms: Respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia, meningitis, skin and soft tissue infections, bone and joint infections, endometritis and other infections in the genital tract. MAGNEX® FORTE is indicated for a specific subset of patients (patients with immunocompromised febrile neutropenic cancer, patients who have undergone a bone marrow transplant).1

Resistance Rate

Cefoperazone/Sulbactam is more efficient in the treatment of uraemic patients with pulmonary infection compared with cefoperazone, which does not increase adverse reactions and is well tolerated2

  

Resistance Rates of Common* Gram-negative Bacteria in AECOPD Lower RTIs (%)2

  

Adapted from Hu F, et al. 2016.


*Comparison between cefoperazone/sulbactam, imipenem, ceftazidime and piperacillin/tazobactam. Based on a surveillance study conducted in Mainland China.1​​​​​​​


​​​​​​​AECOPD, acute exacerbation of chronic obstructive pulmonary disease; RTI, respiratory tract infection.​​​​​​​

References :

Magnex: Local product document. Pfizer; 2020. Version LPDMGX042020.​​​​​​​Hu F, Zhu D, Wang F, et al. Report of CHINET antimicrobial resistance surveillance program in 2015. Chin J Infect Chemother. 2016;16(6):685-694.​​​​​​​
​​​​​Please click the Prescribing Information link to view the safety and adverse events information of MAGNEX®.
For the use only of registered medical practitioner, or a hospital or a laboratory.
PP-MGX-IND-0555 June 2022
Respiratory Tract Infection


About

Cefoperazone/Sulbactam: ​​​​​​​Extended coverage with β-lactamase inhibition​​​​​​

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Dosing

Recommended dosage in adult ​​​​​​and special population​​​​​​​

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Safety

Explore the safety profile of cefoperazone/sulbactam

Review safety profile


Clinical & Scientific Data

Cefoperazone/Sulbactam is more efficient in the treatment ​​​​​​​of infection​​​​​​​

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These pages are not intended for patients or for members of the general public. The web pages contain promotional content. For the use only of Registered Medical Practitioners or a Hospital or a Laboratory. Full prescribing information available on request. For more details on, Who is a Registered Medical Practitioner, please visit "https://cdsco.gov.in/opencms/export/sites/CDSCO_WEB/Pdf-documents/acts_rules/2016DrugsandCosmeticsAct1940Rules1945.pdf", Page No. 39, Rule 2 part (ee), last accessed on 26th April2021.
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Address: The Capital, A Wing, 1802, 18th Floor, Plot No. C-70, 'G' Block, Bandra Kurla Complex, Bandra East, Mumbai - 400051.


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