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Efficacy & SafetyClinical Efficacy RARapid Data (ACR20)Head-to-Head Noninferiority Data (ACR50)Biologics DataClinical Efficacy PsAACR20 DataPASI75 DataEnthesitis and Dactylitis DataClinical Efficacy UC8-week EfficacyOnset of Action Data52-week EfficacyOCTAVE Study DesignSafety and TolerabilitySafety in RASafety in PsASafety in UCResources & SupportResources & SupportMaterialsVideosSummary of Prescribing Information

Early Onset of Efficacy

Clinical studies – RA1

   

The tofacitinib clinical development programme included 2 dose-ranging trials and 5 confirmatory trials. Although other doses have been studied, the recommended dose of tofacitinib is 5 mg BID. 

   

Percentage of ACR20 Responders by Visit for Study IV

   

   

Non-responder imputation was used. Patients who withdrew from the study were counted as failures, as were patients who failed to have at least a 20% improvement in joint counts at Month 3.


Adapted from Xeljanz. Local product document. 2022.

   

   

ACR20, American College of Rheumatology; ADA, adalimumab; PBO, placebo; RA, rheumatoid arthritis.

   

Reference:

Xeljanz. Local product document. Pfizer; 2022. Version LPDTOFA012022.

   

Please click the Prescribing Information link to view the safety and adverse events information of Xeljanz®.
For the use only of Registered Medical Practitioners or a Hospital or a Laboratory.


PP-XEL-IND-0843 22/07/22

Clinical Efficacy in RA

About

XELJANZ® (tofacitinib citrate) is a small molecule that selectively targets the JAK pathway

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Dosing & Administration

   

Helps protect against RA, PsA and UC

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