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XELJANZ® (tofacitinib citrate) delivered a rapid reduction in stool frequency in as early as 2 weeks1
XELJANZ® (tofacitinib citrate) 10 mg BID achieved a statistically significant reduction in the stool frequency subscore* versus placebo2
Pooled Data From OCTAVE 1 and OCTAVE 2 Induction Studies2
Adapted from Data on file. Pfizer Inc.
P values obtained from linear mixed-effects model. Efficacy data are full analysis sets with observed cases.1
*The Mayo stool frequency subscore is a patient-reported measure of disease activity that ranges from 0 to 3 (0 = normal, 1 = 1-2 stools/day more than normal, 2 = 3-4 stools/day more than normal, 3 = >5 stools/day more than normal or 1).3
XELJANZ® (tofacitinib citrate) delivered a rapid reduction in rectal bleeding in as early as 2 weeks1
XELJANZ 10 mg BID significantly reduced the rectal bleeding subscore* versus placebo
Pooled Data From OCTAVE 1 and OCTAVE 2 Induction Studies2
Adapted from Data on file. Pfizer Inc.
P values obtained from linear mixed-effects model. Efficacy data are full analysis sets with observed cases.1
*The Mayo rectal bleeding subscore is a patient-reported measure of disease activity that ranges from 0 to 3 (0 = none, 1 = streaks of blood visible with stool in less than half the time, 2 = blood visible in stool in more than half the time, 3 = blood passed without stool).3
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BID, twice daily; LS, least square; OCTAVE, Operationally Critical Threat, Asset and Vulnerability Evaluation.
References:
Please click the Prescribing Information link to view the safety and adverse events information of Xeljanz®.
For the use only of Registered Medical Practitioners or a Hospital or a Laboratory.
PP-XEL-IND-0843 22/07/22
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For more details on, Who is a Registered medical practitioner*, please visit https://cdsco.gov.in/opencms/export/sites/CDSCO_WEB/Pdf-documents/acts_rules/2016DrugsandCosmeticsAct1940Rules1945.pdf , Page No. 39, Rule 2 part (ee), last accessed on 26th April 2021.
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