ZINFORO®: MoA in the treatment of cSSTI
MoA in cSSTI treatment
ZINFORO®: Potent bactericidal activity against resistant isolates with high binding affinity to
mutated beta-lactam-binding proteins1-6
ZINFORO® binds with high affinity to MRSA PBP2a and MSSA PBPs1-3,6:
How does ZINFORO® exert bacterial activity?
ZINFORO® exerts potent bactericidal activity in cSSTI against resistant isolates with high binding affinity to mutated beta-lactam-binding proteins.1-6
It enforces bactericidal activity in CAP against resistant isolates with high binding affinity in S. pneumoniae.1,2,5
CAP, community-acquired pneumonia; cSSTI, complicated skin and soft tissue infection; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-susceptible Staphylococcus aureus; PBP, penicillin-binding protein; PBP2, penicillin-binding protein 2; PBP2a, penicillin-binding protein 2a.
References:
Example
Simple dosing with a flexible infusion time
Proven clinical efficacy in patients with
CAP and cSSTI
Safety profile consistent with other cephalosporins
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