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DosingRecommended dose modificationsDose Administration

Monitoring

During treatment, appropriate determination of FIX levels is advised to guide the dose to be administered and the frequency of repeated infusions.1
 
Individual patients may vary in their response to FIX, demonstrating different half-lives and recoveries.1
Dose based on body weight may require adjustment in underweight or overweight patients.1
In the case of major surgical interventions in particular, precise monitoring of the substitution therapy by means of coagulation (FIX plasma activity) is indispensable.1
When using an in vitro thromboplastin time (aPTT)-based one stage clotting assay for determining FIX activity in patients' blood samples, plasma FIX activity results can be significantly affected by both the type of aPTT reagent and the reference standard used in the assay. This is of importance particularly when changing the laboratory and/or reagents used in the assay.1

   

   

FIX, factor IX.

   

Reference:

Local product document, Nonacog alfa (recombinant coagulation factor IX), BeneFIX® : LPDBEN062022.

   

PP-BEN-IND-0038 June 2023


Efficacy and Safety

Real-world Data

See how BeneFIX® performs in real-life settings.

Review real-world data

About

BeneFIX® is a recombinant coagulation FIX. Find out how BeneFIX® works

Learn more


Dosing

BeneFIX® provides dosing options based on individual needs

Learn more


Real-world Data

See how BeneFIX® performs in real-life settings.

Review real-world data

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Address: The Capital, A Wing, 1802, 18th Floor, Plot No. C-70, 'G' Block, Bandra Kurla Complex, Bandra East, Mumbai - 400051.


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