Enbrel® is a soluble TNFR fusion protein1
Enbrel® is the only fully human soluble TNFR2
Enbrel® works like a naturally occurring soluble TNFR and inhibits TNF.2
*Mean half-life of approximately 4.3 days (70–100 hours)
†PASI 75 improvements were seen as early as 2 weeks with etanercept 25 mg BIW and 50 mg BIW5.
Disclaimer: The approved dose for Psoriasis is etanercept 25 mg BIW or 50 mg OW and 50 mg BIW can be used upto 12 weeks followed by 25 mg BIW/ 50 mg OW.
AS, ankylosing spondylitis; Fc, fragment crystallisable; IgG1, immunoglobulin G1; PASI, Psoriasis Area and Severity Index; PsA, psoriatic arthritis; PsO, psoriasis; QoL, quality of life; RA, rheumatoid arthritis; TNF, tumour necrosis factor; TNF-α, tumour necrosis factor alpha; TNFR, tumour necrosis factor receptor.
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For more details on, Who is a Registered medical practitioner*, please visit https://cdsco.gov.in/opencms/export/sites/CDSCO_WEB/Pdf-documents/acts_rules/2016DrugsandCosmeticsAct1940Rules1945.pdf , Page No. 39, Rule 2 part (ee), last accessed on 26th April 2021.
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