Congenital hemophilia is a lifelong condition that requires constant and careful management.1 The most common type of hemophilia is called hemophilia A and a less common type is called hemophilia B – both of which are caused by a deficiency in a particular clotting factor (VIII and IX, respectively).2
Prevalence
Hemophilia is quite rare; about 1 in 10,000 people are born with it.2
Causes of Hemophilia
Hemophilia is usually inherited. Inherited hemophilia is caused by a genetic mutation that mainly affects males.2,3
The chances of a child inheriting hemophilia depends on their gender and which parent has the mutated gene.2,3
Non-inherited hemophilia is known as 'sporadic hemophilia' and accounts for approximately one-third of all hemophilia cases. Sporadic hemophilia occurs in people with no family history of hemophilia, where the gene mutation occurs spontaneously rather than being inherited.2
FVIII, factor VIII; FIX, factor IX.
References:
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