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Burden of Disease

Burden of Disease

Description of the DiseaseGlobal EpidemiologyIndian EpidemiologyPneumococcal Disease and InfluenzaChallenges

Risk Factors
 

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Secondary Infections
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Prevention of Pneumococcal Disease
 

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Need for Pneumococcal Vaccination

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Cost-effectiveness of PCV13
 

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Effectiveness of Prevenar 13® 
 

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Indian Clinical Trials
 

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Recommendations for Use

Recommendations for Use
 

ACIP 2019NCCN 2020RSSDI 2020IMA GuidelinesIAOH Guidelines for Working AdultsClinical Practice Guidelines 2019 (ICS/NCCP)The Geriatric Society of India, 2015Indian Society of Nephrology
FAQs

PCV13 in Pulmonology
 

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PCV13 in Nephrology
 

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PCV13 in Oncology
 

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PCV13 in Rheumatology
 

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PCV13 in Diabetes
 

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The Indian Society Of Nephrology

The Indian society of Nephrology released its guidelines in 2016 for the vaccination of patients with CKD and kidney transplant recipients.

   

Recommendations for Patients With CKD

   

Patients with CKD over the age of 50 should receive a dose of PCV13 first, followed by a dose of PPSV23 at least 8 weeks later. Subsequent doses of PPSV23 should follow current PPSV23 recommendations for adults at high risk. The guidelines also mention that the burden of pneumococcal infections in patients with CKD is high, the cost of pneumococcal vaccination is low as compared with the global health costs in this population and there are no data indicating potential disadvantages. Thus, pneumococcal vaccination should be administered to all patients with CKD as early in the disease as possible. The schedule of vaccination to be followed in all patients with CKD is given below.

   

Recommendations for Administering PCV13 and PPSV23 Vaccines for Patients With CKD1

   

Adapted from Guidelines for vaccination in patients with chronic kidney disease. 2016.

Recommendations for Transplant Patients

In case of kidney transplant patients, the guidelines advise that the schedule of immunisation with the vaccines to be followed is as per the recommended schedule for general adults. However, owing to intense immunosuppression following kidney transplant, vaccination should be avoided within 3 to 6 months of transplantation. In addition, for preventing infection in kidney transplant patients, pneumococcal vaccines should be administered to all household contacts, including pets, of the transplant recipients. The ACIP guidelines suggest the following comprehensive approach for optimal vaccine efficacy among immunocompromised adults, which includes kidney transplant recipients:

  • If a patient receives the first dose of PCV13, it should be followed by PPSV23 about 8 weeks later1

  • If a patient had received PPSV23 in the past, a PCV13 dose should be administered after at least a year only1

  • If a patient who has received PPSV23 requires further doses of PPSV23, it should be administered at least 5 years after the last dose of PPSV231

   

CKD, chronic kidney disease; PCV-7, 7-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine; PPSV23, 23-valent pneumococcal plain polysaccharide vaccine.

  

Reference:

Guidelines for vaccination in patients with chronic kidney disease. Indian J Nephrol. 2016;26(Suppl 1):S15-S18.

   

Please click the Prescribing Information link to view the safety and adverse events information of Prevenar 13®.
For the use only of Registered Medical Practitioners or a Hospital or a Laboratory.

   

PP-PRV-IND-0268 July 2022

Recommendations for Use

Dosing

Help protect your adult patients against pneumococcal pneumonia with single-dose administration

Learn more

   

Efficacy

Efficacy proven by the CAPiTA study

Learn more

   

Recommendations for Use

The ACIP recommends routine use of PCV13 among adults

Learn more

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