Enbrel® is approved across 6 indications, including paediatric indications.¹
Moderate to severe RA
Enbrel®, alone or in combination with MTX, has been shown to reduce the rate of progression of joint damage, as measured by an X-ray, and to improve physical function.3
Enbrel® provides long-term RA control
LORHEN6
Adapted from Marchesoni A, et al. 2009.
P = 0.027 Enbrel versus, Adalimumab and Infliximab. Not a head to head comparison.
GISEA7
Adapted from Iannone F, et al. 2012.
P<0.0001 for Enbrel® versus other treatment groups. Not a head-to-head comparison.
Numerically, more patients continued on Enbrel® at 6 months to 5 years than on adalimumab or infliximab.8
Number of patients evaluated (number of studies included)
Adapted from Arora A, et al. 2013.
Pooled drug survival rate. Biologic-naïve group. Not a head-to-head comparison. There were differences in baseline characteristics of patients among different registries.9
An RA patient with an increased risk of serious infections
An MTX-IR patient
An RA patient considering starting a family
An elderly-onset RA patient
A young patient worried about the lifelong impact of RA
A young RA patient worried about treatments that lose effectiveness over time
ADA, adalimumab; COPD, chronic obstructive pulmonary disease; DMARD, disease-modifying antirheumatic drug; EMA, European Medicines Agency; ETN, etanercept; GISEA, Gruppo Italiano Studio Early Arthritis; INF, infliximab; LORHEN, Lombardy Rheumatology Network; MTX, methotrexate; MTX-IR, methotrexate-inadequate responder; RA, rheumatoid arthritis; TNFi, tumour necrosis factor inhibitor.
References:
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